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The PROMIS-29 Is Valid for Use in Older Adults with Multiple Chronic Condition

• Scores on the PROMIS-29 are valid for use in an older population with MCC.
• Using data collected at baseline and a six-month follow-up, PMs based on the VR-36 or PROMIS-29 would have required infeasible or impossible sample sizes to achieve acceptable reliability for performance measurement.
• A major limitation of the approach taken here was the small amount of change in health-related quality of life (HRQoL) that can be expected over a six-month interval.
• It is feasible to collect HRQoL data among older adults with MCC in an integrated health system, but additional work is needed before such data can be used as a basis for performance measurement.