G2TT
来源类型Research Reports
规范类型报告
DOIhttps://doi.org/10.7249/RR2503
来源IDRR-2503-BIOG
Assessing the Preparedness of the Health Care System Infrastructure in Six European Countries for an Alzheimer's Treatment
Jakub P. Hlavka; Soeren Mattke; Jodi L. Liu
发表日期2018
出版年2018
页码24
语种英语
结论
  • The burden of Alzheimer's disease in high-income countries is expected to approximately double between 2015 and 2050. Recent clinical trial results give hope that a disease-modifying therapy might become available in the near future. The therapy is expected to treat early-stage patients to prevent or delay the progression to dementia.
  • This preventive treatment paradigm implies the need to screen, diagnose, and treat a large population of patients with mild cognitive impairment. There would be many undiagnosed prevalent cases that would need to be addressed initially, and then the longer-term capacity to address incident cases would not need to be as high.
  • We use a simulation model to assess the preparedness of the health care system infrastructure in six European countries — France, Germany, Italy, Spain, Sweden, and the United Kingdom — to evaluate, diagnose, and treat the expected number of patients.
  • Projected peak wait times range from five months for treatment in Germany to 19 months for evaluation in France. The first year without wait times would be 2030 in Germany and 2033 in France, and 2042 in the United Kingdom and 2044 in Spain. Specialist capacity is the rate-limiting factor in France, the United Kingdom, and Spain, and treatment delivery capacity is an issue in most of the countries.
  • If a disease-modifying therapy becomes available in 2020, we estimate the projected capacity constraints could result in over 1 million patients with mild cognitive impairment progressing to Alzheimer's dementia while on wait lists between 2020 and 2050 in these six countries.
摘要
  • In addition to increasing specialist and infusion capacity in each individual country, joint actions and planning in Europe can help provide better coordinated and more timely care for Alzheimer's patients.
  • A combination of reimbursement, regulatory, and workforce planning policies, as well as innovation in diagnosis and treatment delivery, is needed to expand capacity and to ensure that available capacity is leveraged optimally to treat patients with early-stage Alzheimer's disease.
主题Alzheimer's Disease and Dementias ; France ; Germany ; Health Care Services Capacity ; Italy ; Mental Health Treatment ; Spain ; Sweden ; United Kingdom
URLhttps://www.rand.org/pubs/research_reports/RR2503.html
来源智库RAND Corporation (United States)
引用统计
资源类型智库出版物
条目标识符http://119.78.100.153/handle/2XGU8XDN/108852
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Jakub P. Hlavka,Soeren Mattke,Jodi L. Liu. Assessing the Preparedness of the Health Care System Infrastructure in Six European Countries for an Alzheimer's Treatment. 2018.
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