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With the implementation of the nuclear agreement with Iran (known as the Joint Comprehensive Plan of Action, or JCPOA) on January 16, 2016, the RAND Center for Middle East Public Policy (CMEPP) organized a conference to pose the question, "Will the Iran deal survive?" These video conference proceedings present panel discussions from the daylong conference, which took place on March 3, 2016, in the Washington office of the RAND Corporation, and consider current and future challenges facing the agreement and broader implications for Iran, the region, and U.S. policy.