G2TT
来源类型Monograph (IIASA Interim Report)
规范类型报告
Quantitative-Genetic Models and Changing Environments.
Buerger R; Krall C
发表日期2004
出版者IIASA, Laxenburg, Austria: IR-04-062
出版年2004
语种英语
摘要Mutation is the ultimate source of genetic variability. However, a large fraction of mutations reduce the fitness of the individuals in which they occur (Chapter 7). The evolutionary consequences of mutations with an unconditionally deleterious effect are manifold and have been the subject of intense investigation (Charlesworth and Charlesworth 1998; Chapter 9). Since many mutations affect several traits and the developmental pathways are complex, their fitness effects may also depend on the genetic background in which they occur, and on the kind of selective pressure to which the population is exposed. For instance, if for a given trait, say birth weight, there is an optimal phenotype, a mutation that increases birth weight will be detrimental if it arises in a genotype that, otherwise, would have the optimal or a higher birth weight, but will be beneficial in other genotypes. In a changing environment, the selective value of an allele will change with time if different values of a trait affected by the allele are favored at different times. The fitness effect of a given mutation, therefore, depends on the effect it has on this trait, and on the current environment. Hence, a newly introduced allele may, in spite of its immediate adversary effect on fitness, prove to be beneficial at a later stage of the population history. Mutation itself thereby gains an additional role as a provider of the genetic variation that allows adaptation to occur.
主题Adaptive Dynamics Network (ADN)
URLhttp://pure.iiasa.ac.at/id/eprint/7387/
来源智库International Institute for Applied Systems Analysis (Austria)
资源类型智库出版物
条目标识符http://119.78.100.153/handle/2XGU8XDN/125313
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Buerger R,Krall C. Quantitative-Genetic Models and Changing Environments.. 2004.
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