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来源类型Article
规范类型其他
DOI10.1007/BF00275995
Dependent competing risks: a stochastic process model.
Yashin A; Manton KG; Stallard E
发表日期1986
出处Journal of Mathematical Biology 24 (2): 119-140
出版年1986
语种英语
摘要Analyses of human mortality data classified according to cause of death frequently are based on competing risk theory. In particular, the times to death for different causes often are assumed to be independent. In this paper, a competing risk model with a weaker assumption of conditional independence of the times to death, given an assumed stochastic covariate process, is developed and applied to cause specific mortality data from the Framingham Heart Study. The results generated under this conditional independence model are compared with analogous results under the standard marginal independence model. Under the assumption that this conditional independence model is valid, the comparison suggests that the standard model overestimates by 4% the effect on life expectancy at age 30 due to the hypothetical elimination of cancer and by 7% the effect for cardiovascular/cerebrovascular disease. By age 80 the overestimates were 11% for cancer and 16% for heart disease. These results suggest the importance of avoiding the marginal independence assumption when appropriate data are available - especially when focusing on mortality at advanced ages.
关键词Chronic disease Cohort study Diffusion Framingham heart study Human mortality Maximum likelihood Mortality selection Survival with covariates
URLhttp://pure.iiasa.ac.at/id/eprint/13648/
来源智库International Institute for Applied Systems Analysis (Austria)
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资源类型智库出版物
条目标识符http://119.78.100.153/handle/2XGU8XDN/126948
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GB/T 7714
Yashin A,Manton KG,Stallard E. Dependent competing risks: a stochastic process model.. 1986.
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