全球智库信息集成服务系统(G2TT): Declining trends in conception rates in recent birth cohorts of native Danish women: A possible role of deteriorating male reproductive health.

G2TT

来源类型	Article
规范类型	其他
DOI	10.1111/j.1365-2605.2007.00827.x
	Declining trends in conception rates in recent birth cohorts of native Danish women: A possible role of deteriorating male reproductive health.
	Kold Jensen T; Sobotka T; Hansen MA; Tonnes Pedersen A; Lutz W; Skakkebaek NE
发表日期	2008
出处	International Journal of Andrology 31 (2): 81-92
出版年	2008
语种	英语
摘要	Recent findings of poor semen quality among at least 20% of normal young men in Denmark prompted us to use unique Danish registers on births and induced abortions to evaluate a possible effect of the poor male fecundity on pregnancy rates among their presumed partners - the younger cohorts of women. We have analysed data from the Danish birth and abortion registries as well as the Danish registry for assisted reproduction (ART) and defined a total natural conception rate (TNCR), which is equal to fertility rate plus induced abortion rate minus ART conception rate. A unique personal identification number allowed the linkage of these databases. Our database included 706270 native Danish women born between 1960 and 1980. We used projections to estimate the fertility of the later cohorts of women who had not yet finished their reproduction. We found that younger cohorts had progressively lower TNCR and that in terms of their total fertility rate, the declining TNCR is is compensated by an increasing use of ART. Our hypothesis of an ongoing birth cohort-related decline in fecundity was also supported by our finding of increasing and substantial use of ART in the management of relatively young couples in the later cohorts. Furthermore, the lower rates of induced abortion among the younger birth cohorts, often viewed as a success of health education programs, may not be fully explained by improved use of contraception. It seems more likely that decreased fecundity because of widespread poor semen quality among younger cohorts of otherwise normal men may explain some of the observed decline in conception rates. This may imply increasing reproductive health problems and lower fertility in the future, which is difficult to reverse in the short term. The current and projected widespread use of ART in Denmark may be a sign of such an emerging public health problem.
主题	World Population (POP)
关键词	Fertility rate Male reproductive health Total natural conception rate
URL	http://pure.iiasa.ac.at/id/eprint/8610/
来源智库	International Institute for Applied Systems Analysis (Austria)
引用统计
资源类型	智库出版物
条目标识符	http://119.78.100.153/handle/2XGU8XDN/128885
推荐引用方式 GB/T 7714	Kold Jensen T,Sobotka T,Hansen MA,et al. Declining trends in conception rates in recent birth cohorts of native Danish women: A possible role of deteriorating male reproductive health.. 2008.