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The theory on the geography of innovation indicates that peripheral regions suffer from structural disadvantage, as the emergence of innovation tends to diminish with the distance from metropolitan areas. A series of indicators, variables, and models presented in the study, confirm this tendency in Israel. Despite the gap, there is an increase in innovative activity in the periphery, in particular in the fields of high technology. This could attributed to government policy, which in recent years has increased its support of innovative activity in the periphery. However, it is not clear whether sufficient support is given, in light of the needs and limitations of the periphery, as shown by the study.

The study recommends possible policy directions, mainly aimed at establishing a regional innovation authority that will be responsible for forming and updating an innovation database focusing on the periphery. This database is necessary for policy-making outlined by this regional authority.