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We spend more than 2/3rds of our time where we live; thus, housing and neighborhood conditions invariably affect our individual and family’s well-being. The health impacts from blighted properties—substandard housing, abandoned buildings, and vacant lots—are often not immediately visible or felt. This report—Urban Blight and Public Health—synthesizes recent studies on the complexities of how blight affects the health of individuals and neighborhoods while offering a blend of policy and program recommendations to help guide communities in taking a more holistic and coordinated approach, such as expanding the use of health impact assessments, tracking health outcomes, and infusing public health into housing policies, codes and practices.