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This conference was held at Chatham House to initiate a series of meetings organized by the Centre on Global Health Security to address the problem of antimicrobial resistance. The conference and series of roundtables aim to address, in particular, the following key issues:

• What new efforts by governments and stakeholders in the developing and developed world are needed for global antimicrobial conservation? What obstacles constrain effective action? How can they be addressed?
   
• What are the most efficient ways of stimulating new drug development for long-term sustainability? What has been tried? What is most likely to work? What does this mean for government policies?
   
• How do we address antibiotic use in the food and agriculture sector (including fisheries)? How do we promote cross-sectoral collaboration? What are the obstacles? How can they be overcome?