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Climate change in addition to food insecurity is among the key problems facing Nigeria.  Scientific evidence shows that climate change is affecting grain yield in Nigeria.  Also, Nigeria is currently ranked 84th out of 119 countries on the 2017 global hunger index. Therefore, there is need to evolve evidence-based policies to tackle climate change and enhance food security. Climate-smart agricultural (CSA) technologies, practices and services are proven means of reducing green house gas emissions and enhancing food production. To formulate and strengthen policy initiatives to enhance CSA, this study estimates the determinants of use of climate smart agricultural practices in Nigeria and the impact of use on farmer’s net revenue and poverty (measured as expenditure per capita). Three CSA agricultural practices we will consider are having/planting trees on plot (agroforestry) (T), irrigation on plot (I) and mixed cropping/intercropping with legume (cowpea) on plot (M). The three technologies will give eight alternative packages possible for adoption as follows: T0I0M0, T1I0M0, T0I1M0, T0I0M1, T1I1M0, T0I1M1, T1I0M1 and T1I1M1. Nigeria General Household Survey (GHS) panel data waves 1, 2 and 3 collected in 2011/2012, 2013/2014 and 2015/2016 will be used for the study. We will apply multinomial endogenous switching regression (MESR) model to estimate the determinants of use of CSA practices and the impacts of use on net crop revenue and poverty measured as expenditure per capita. At the end of the study, determinants of CSA practices and its impact on farmer’s net revenue and per capita expenditure will be known. Also, policy briefs, hand bills and flyers will be developed for interaction with policy makers, farmers and other stakeholders to facilitate uptake.