| 来源类型 | Working Paper |
| 规范类型 | 报告 |
| DOI | 10.3386/w11288 |
| 来源ID | Working Paper 11288 |
| Advanced Purchase Commitments for a Malaria Vaccine: Estimating Costs and Effectiveness | |
| Ernst R. Berndt; Rachel Glennerster; Michael R. Kremer; Jean Lee; Ruth Levine; Georg Weizsacker; Heidi Williams | |
| 发表日期 | 2005-05-02 |
| 出版年 | 2005 |
| 语种 | 英语 |
| 摘要 | To overcome the problem of insufficient research and development (R&D) on vaccines for diseases concentrated in low-income countries, sponsors could commit to purchase viable vaccines if and when they are developed. One or more sponsors would commit to a minimum price that would be paid per person immunized for an eligible product, up to a certain number of individuals immunized. For additional purchases, the price would eventually drop to short-run marginal cost. If no suitable product were developed, no payments would be made. We estimate the offer size which would make the revenues from R&D investments on a malaria vaccine similar to revenues realized from investments in typical existing commercial pharmaceutical products, as well as the degree to which various contract models and assumptions would affect the cost-effectiveness of such a commitment for the case of a malaria vaccine. Under conservative assumptions, we document that the intervention would be highly cost-effective from a public health perspective. Sensitivity analyses suggest most characteristics of a hypothetical malaria vaccine would have little effect on the cost-effectiveness, but that the duration of protection against malaria conferred by a vaccine strongly affects potential cost-effectiveness. Readers can conduct their own sensitivity analyses employing a web-based spreadsheet tool. |
| 主题 | Health, Education, and Welfare ; Health ; Development and Growth ; Development ; Innovation and R& ; D |
| URL | https://www.nber.org/papers/w11288 |
| 来源智库 | National Bureau of Economic Research (United States) |
| 引用统计 | |
| 资源类型 | 智库出版物 |
| 条目标识符 | http://119.78.100.153/handle/2XGU8XDN/568926 |
| 推荐引用方式 GB/T 7714 | Ernst R. Berndt,Rachel Glennerster,Michael R. Kremer,et al. Advanced Purchase Commitments for a Malaria Vaccine: Estimating Costs and Effectiveness. 2005. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 资源类型 | 版本类型 | 开放类型 | 使用许可 | ||
| w11288.pdf（159KB） | 智库出版物 | 限制开放 | CC BY-NC-SA | 浏览 | ||
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