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来源类型Working Paper
规范类型报告
DOI10.3386/w12906
来源IDWorking Paper 12906
Anti-depressants and Suicide
Jens Ludwig; Dave E. Marcotte; Karen Norberg
发表日期2007-02-16
出版年2007
语种英语
摘要Does drug treatment for depression with selective serotonin reuptake inhibitors (SSRIs) increase or decrease the risk of completed suicide? The question is important in part because of recent government warnings that question the safety of SSRIs, one of the most widely prescribed medications in the world. While there are plausible clinical and behavioral arguments that SSRIs could have either positive or negative effects on suicide, randomized clinical trials have not been very informative because of small samples and other problems. In this paper we use data from 26 countries for up to 25 years to estimate the effect of SSRI sales on suicide mortality using just the variation in SSRI sales that can be explained by cross-country variation in the growth of drug sales more generally. We find that an increase in SSRI sales of 1 pill per capita (about a 12 percent increase over 2000 sales levels) is associated with a decline in suicide mortality of around 5 percent. These estimates imply a cost per statistical life far below most other government interventions to improve health outcomes.
主题Health, Education, and Welfare ; Health
URLhttps://www.nber.org/papers/w12906
来源智库National Bureau of Economic Research (United States)
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资源类型智库出版物
条目标识符http://119.78.100.153/handle/2XGU8XDN/570572
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GB/T 7714
Jens Ludwig,Dave E. Marcotte,Karen Norberg. Anti-depressants and Suicide. 2007.
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