| 来源类型 | Working Paper |
| 规范类型 | 报告 |
| DOI | 10.3386/w18918 |
| 来源ID | Working Paper 18918 |
| Price Indexes for Clinical Trial Research: A Feasibility Study | |
| Ernst R. Berndt; Iain M. Cockburn | |
| 发表日期 | 2013-03-21 |
| 出版年 | 2013 |
| 语种 | 英语 |
| 摘要 | We estimate hedonic price indexes for clinical trial research, an important component of biomedical R&D, using a large sample of agreements between trial sponsors and clinical investigators obtained from Medidata Solutions Worldwide Inc. Nominal prices measured as total grant cost per patient rose by a factor of 4.5 between 1989 and 2011, while the NIH Biomedical R&D Price Index (BRDPI) focused on input costs rose only 2.2-fold. Most of the disparity appears to be attributable to changes in the nature and organization of clinical trials: during this period the average number of patients per site fell substantially while "site work effort" more than doubled. After controlling for these changes in the characteristics of investigator agreements using a variety of methods based on hedonic regressions, we find that the estimated rate of inflation in clinical trials costs tracks the BDRPI very closely. Results from this study suggest that it should be feasible for statistical agencies to develop a producer price index for this type of R&D activity, contributing to broader efforts to develop a deflator for contracted R&D services. |
| 主题 | Macroeconomics ; Business Cycles ; Industrial Organization ; Industry Studies ; Development and Growth ; Growth and Productivity |
| URL | https://www.nber.org/papers/w18918 |
| 来源智库 | National Bureau of Economic Research (United States) |
| 引用统计 | |
| 资源类型 | 智库出版物 |
| 条目标识符 | http://119.78.100.153/handle/2XGU8XDN/576593 |
| 推荐引用方式 GB/T 7714 | Ernst R. Berndt,Iain M. Cockburn. Price Indexes for Clinical Trial Research: A Feasibility Study. 2013. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 资源类型 | 版本类型 | 开放类型 | 使用许可 | ||
| w18918.pdf（765KB） | 智库出版物 | 限制开放 | CC BY-NC-SA | 浏览 | ||
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