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来源类型Working Paper
规范类型报告
DOI10.3386/w29786
来源IDWorking Paper 29786
Seeing the Future: A Better Way to Model and Test for Adaptive Developmental Plasticity
Anup Malani; Stacy Rosenbaum; Susan C. Alberts; Elizabeth A. Archie
发表日期2022-02-28
出版年2022
语种英语
摘要Early life conditions can have profound effects on individual health, longevity, and biological fitness. Two classes of hypotheses are used to explain the evolutionary origins of these effects: developmental constraints (DC) hypotheses, which focus on the deleterious effects of low-quality early-life environments, and predictive adaptive response (PAR) models, which focus on organisms’ predictions about their adult environment, phenotypic adaptations based on that prediction, and the deleterious consequences of incorrect predictions. Despite their popularity, these ideas remain poorly defined. To remedy this, we provide mathematical definitions for DC, PARs, and related concepts, and develop statistical tests derived from these definitions. We use simulations to demonstrate that PARs are more readily detected by tests based on quadratic regressions than by tests based on more commonly used interaction regression models. We demonstrate that the poor performance of interaction models stems from two problems: first, they are mathematically incapable of detecting a central prediction of PAR, and second, they conceptually conflate PARs with DC. We conclude by providing recommendations for how researchers can make use of explicit definitions and properly-aligned visualizations and statistical tests to make progress in this important research area.
主题Health, Education, and Welfare ; Health
URLhttps://www.nber.org/papers/w29786
来源智库National Bureau of Economic Research (United States)
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资源类型智库出版物
条目标识符http://119.78.100.153/handle/2XGU8XDN/587460
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Anup Malani,Stacy Rosenbaum,Susan C. Alberts,et al. Seeing the Future: A Better Way to Model and Test for Adaptive Developmental Plasticity. 2022.
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