| 来源类型 | Working Paper |
| 规范类型 | 报告 |
| DOI | 10.3386/w30084 |
| 来源ID | Working Paper 30084 |
| Causal Inference During a Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina | |
| Sebastian Calonico; Rafael Di Tella; Juan Cruz Lopez Del Valle | |
| 发表日期 | 2022-05-30 |
| 出版年 | 2022 |
| 语种 | 英语 |
| 摘要 | Many medical decisions during the pandemic were made without the support of causal evidence obtained in clinical trials. We study the case of nebulized ibuprofen (NaIHS), a drug that was extensively used on COVID-19 patients in Argentina amidst wild claims about its effectiveness and without regulatory approval. We study data on 5,146 patients hospitalized in 11 health centers spread over 4 provinces, of which a total of 1,019 (19.8%) received the treatment. We find a large, negative and statistically significant correlation between NaIHS treatment and mortality using inverse probability weighting estimators. We consider several threats to identification, including the selection of “low” risks into NaIHS, spillovers affecting patients in the control group, and differences in the quality of care in centers that use NaIHS. While the negative correlation appears to be, broadly, robust, our results are best interpreted as emphasizing the benefits of running a randomized controlled trial and the challenges of incorporating information produced in other, less rigorous circumstances. |
| 主题 | Health, Education, and Welfare ; Health ; Development and Growth ; Innovation and R& ; D ; COVID-19 |
| URL | https://www.nber.org/papers/w30084 |
| 来源智库 | National Bureau of Economic Research (United States) |
| 引用统计 | |
| 资源类型 | 智库出版物 |
| 条目标识符 | http://119.78.100.153/handle/2XGU8XDN/587758 |
| 推荐引用方式 GB/T 7714 | Sebastian Calonico,Rafael Di Tella,Juan Cruz Lopez Del Valle. Causal Inference During a Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina. 2022. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 资源类型 | 版本类型 | 开放类型 | 使用许可 | ||
| w30084.pdf（581KB） | 智库出版物 | 限制开放 | CC BY-NC-SA | 浏览 | ||
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