| 来源类型 | Working Paper |
| 规范类型 | 报告 |
| DOI | 10.3386/w30155 |
| 来源ID | Working Paper 30155 |
| NIH Grant Expansion, Ancestral Diversity and Scientific Discovery in Genomics Research | |
| Wei Fu; Shin-Yi Chou; Li-San Wang | |
| 发表日期 | 2022-06-20 |
| 出版年 | 2022 |
| 语种 | 英语 |
| 摘要 | In the approaching era of genomic medicine, the underrepresentation of minority populations in human genetics and genomics research has raised growing concerns regarding the distributive justice in the translation of biomedical innovations into human health across populations. Quantitative assessment of public funding policy in addressing the missing diversity is imperative yet lacking. In this paper, we fill this gap by empirically answering two central questions in the context of Genome-Wide Association Studies (GWAS): whether improved funding opportunity facilitates minority health research, and how significant is the scientific value of funding science on underrepresented populations. Our identification draws on an exogenous NIH grant expansion under the American Reinvestment and Recovery Act of 2009, and exploits variations in the share of people with medical conditions among minorities relative to whites. Our main findings are threefold. First, the ARRA-NIH grant expansion contributes to an increase in the inclusion of minority ancestries in GWAS. It also facilitates the engagement of minority scientists in academic activities and promotes their role in scientific collaborations. The grant expansion fosters the discoveries of disease-associated genetic variants within minority populations. This quantitative evidence speaks to the role that public funding policy can play in advancing science. |
| 主题 | Health, Education, and Welfare ; Health ; Labor Economics ; Demography and Aging ; Development and Growth ; Innovation and R& ; D |
| URL | https://www.nber.org/papers/w30155 |
| 来源智库 | National Bureau of Economic Research (United States) |
| 引用统计 | |
| 资源类型 | 智库出版物 |
| 条目标识符 | http://119.78.100.153/handle/2XGU8XDN/587829 |
| 推荐引用方式 GB/T 7714 | Wei Fu,Shin-Yi Chou,Li-San Wang. NIH Grant Expansion, Ancestral Diversity and Scientific Discovery in Genomics Research. 2022. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 资源类型 | 版本类型 | 开放类型 | 使用许可 | ||
| w30155.pdf（1744KB） | 智库出版物 | 限制开放 | CC BY-NC-SA | 浏览 | ||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
