全球智库信息集成服务系统(G2TT): Ambient ionization mass spectrometry imaging of rohitukine, a chromone anti-cancer alkaloid, during seed development in Dysoxylum binectariferum Hook.f (Meliaceae).,

G2TT

来源类型	Journal Article
规范类型	其他
	Ambient ionization mass spectrometry imaging of rohitukine, a chromone anti-cancer alkaloid, during seed development in Dysoxylum binectariferum Hook.f (Meliaceae).,
	Mohana Kumara P; Amitava Srimany; Ravikanth G; Uma Shaanker R and Pradeep T
发表日期	2015
出处	Phytochemistry 116 (1): 104-110
出版年	2015
语种	英语
摘要	Rohitukine, a chromone alkaloid, possesses anti-inflammatory, anti-cancer and immuno-modulatory properties. It has been reported from four species, belonging to the families, Meliaceae and Rubiaceae. Stem bark of Dysoxylum binectariferum (Meliaceae) accumulates the highest amount of rohitukine (3–7% by dry weight). In this study, we examine the spatial and temporal distribution of rohitukine and related compounds during various stages of seed development in D. binectariferum using desorption electrospray ionization mass spectrometry imaging (DESI MSI). Rohitukine (m/z 306.2) accumulation increased from early seed development to seed maturity stage. The spatial distribution of rohitukine was largely restricted to the cotyledonary tissue followed by the embryo and least in the seed coat. Besides rohitukine, rohitukine acetate (m/z 348.2) and glycosylated rohitukine (m/z 468.2) were also detected, both through mass fragmentation and exact mass analysis through Orbitrap mass spectrometry. These results indicate a dynamic pattern of chromane alkaloid accumulation through seed development in D. binectariferum.
主题	Biodiversity Monitoring and Conservation Planning
URL	https://www.atree.org/node/117
来源智库	Ashoka Trust for Research in Ecology and the Environment (India)
资源类型	智库出版物
条目标识符	http://119.78.100.153/handle/2XGU8XDN/86026
推荐引用方式 GB/T 7714	Mohana Kumara P,Amitava Srimany,Ravikanth G,et al. Ambient ionization mass spectrometry imaging of rohitukine, a chromone anti-cancer alkaloid, during seed development in Dysoxylum binectariferum Hook.f (Meliaceae).,. 2015.